http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2019008416-A

Outgoing Links

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filingDate 2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_702222d40fc455d3fdad767e90b4d4a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2481ab2c7772bf644d60caa04c5278bd
publicationDate 2019-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-2019008416-A
titleOfInvention STABLE LIQUID COMPOSITION INCLUDING BOTULINUM TOXIN.
abstract The present disclosure relates to a stable liquid composition comprising a botulinum toxin as an active ingredient that is ready to use without the need for a reconstitution process, and particularly, to a liquid composition that can prevent the botulinum toxin from being added even when botulinum toxin is contained at a low concentration, so as to exhibit high stability, and efficiently avoid adsorption, etc., to a container, to constantly maintain botulinum toxin activity for each batch or for each vial of liquid. Especially, the present disclosure relates to the liquid composition comprising (i) a botulinum toxin as an active ingredient, (ii) L-alanine or methylcellulose, (iii) a surfactant, and optionally, an isotonic agent. The liquid composition of the botulinum toxin according to the present disclosure is the one that is ready to use without carrying out a reconstitution process, and thus it is possible to improve the convenience of the user, and reduce a drift of the activity of the botulinum toxin, etc., due to dilution errors in the reconstitution process, etc. Furthermore, the liquid composition according to the present disclosure efficiently prevents the botulinum toxin from being added even at a low concentration of the botulinum toxin to thereby have extremely excellent storage stability, and efficiently prevents the adsorption of the toxin. botulinum toxin to a container, thereby maintaining a constant botulinum toxin activity for each batch or vial of liquid.
priorityDate 2017-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 31.