| abstract |
The present invention relates to an improved method for producing a diphenylmethane derivative that is effective as a sodium dependent glucose cotransporter inhibitor (SGLT), the method being performed by means of a convergent synthesis method in which each major group It is synthesized separately and then coupled. As such, in comparison to a linear synthesis method described in existing documents, the synthesis pathway is compact and the yield can be increased, and the risk factors inherent in the linear synthesis pathway can be reduced. In addition, the crystalline form of the compound produced in accordance with the method has excellent physicochemical characteristics and, therefore, can be used effectively in fields such as the manufacture of pharmaceutical products. |