abstract |
A method of treating an inflammatory disorder in a subject, comprising administering to the subject in need a nucleic acid molecule to inhibit the expression of Hom-1. Specifically, the nucleic acid molecule is an RNAi agent or an antisense morpholino oligonucleotide. In addition, a method is described for selecting a therapeutic agent for an inflammatory disorder in a subject, or monitoring the efficacy of a therapeutic agent for an inflammatory disorder in a subject, which comprises detecting the level of Hom-1 expression in a sample of inflamed tissue obtained from the subject. |