http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2017011013-A

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filingDate 2016-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffab9e9916c437c80b3fde412a8e0a23
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publicationDate 2018-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-2017011013-A
titleOfInvention OLIGONUCLEOTID THERAPY FOR CONGENITE AMBERURISE OF LAW.
abstract Antisense oligonucleotides focus on intron 26 mutation of the CEP290 gene and reduce the inclusion of aberrant exon in the CEP290 mRNA. Oligonucleotides include no more than 3 consecutive guanosines, do not have more than 60% guanosine nucleobases, include at most a CpG sequence and / or do not have the potential to form a hairpin comprising 3 or more complementary base pairs.
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