http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2017009913-A

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filingDate 2016-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6b2b8eb8571b6aa5e3020a2e8fb6671
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_705d2343b158d1fbf1a29db5fc539799
publicationDate 2018-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-2017009913-A
titleOfInvention LIOFILIZED COMPOSITIONS OF HIGH AREA AREA THAT INCLUDE ARSENIC FOR ORAL ADMINISTRATION IN PATIENTS.
abstract The present invention relates to the treatment of malignancies such as tumors or cancers by oral administration of lyophilized compositions comprising arsenic to a subject in such need. Malignancies include different hematological malignancies, such as acute myeloid leukemia (AML) including acute promyelocytic leukemia (APL), myelodysplastic syndrome (MDS), multiple myeloma (MM) and solid lymphomas and tumors including glioblastoma multiforme and breast cancer. Arsenic treatment has shown to be very promising in the treatment of several cancers but requires daily intravenous (IV) administration. This invention relates to a novel formulation comprising a lyophilized composition comprising arsenic. As a result, the formulation facilitates a systemic bioavailability comparable to that of the intravenous (IV) administration of arsenic trioxide that is currently practiced. The present invention also relates to a method for lyophilizing arsenic trioxide, preparing the oral formulation comprising lyophilized compositions comprising arsenic, and a method for treating a subject with malignancies using the oral formulation.
priorityDate 2015-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 34.