http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2017009643-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68c213ba9952360f439567152e047b18 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 |
filingDate | 2016-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c487d2893b0ea405934bd831f4d9661b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a859abfc1a4da26e61f98f378d38df8 |
publicationDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | MX-2017009643-A |
titleOfInvention | COMPOSITIONS AND METHODS OF USE OF THYROSINE KINASE INHIBITORS. |
abstract | The present invention provides compositions and methods for inhibiting tyrosine phosphorylation; In one aspect, a composition includes including a low dose tyrosine kinase inhibitor, where the low dose tyrosine kinase inhibitor decreases tyrosine phosphorylation; In another aspect, a method for treating a cardiovascular disease or condition associated with a rasopathy having an aberrant phosphorylation of the tyrosine protein is described; Methods for treating congenital heart disease associated with Noonan syndrome or Noonan syndrome with multiple lentigos and decreased aberrant levels of tyrosyl phosphorylation of the related zero protein (PZR) are also described. |
priorityDate | 2015-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.