abstract |
The present invention provides novel pharmaceutical compositions of dimethyl fumarate; The pharmaceutical compositions of the present invention are in the form of a bead and comprise (i) an inert core; (ii) a first layer surrounding the inert core, wherein the first layer comprises dimethyl fumarate; and (iii) an enteric coating that surrounds the first layer; Pharmaceutical compositions are also provided in the form of a bead comprising a core and an enteric coating surrounding the core, wherein the core comprises dimethyl fumarate; Methods of using the pharmaceutical compositions of the present invention to treat multiple sclerosis are also included. |