| abstract |
The present invention relates to a process for preparing a biomaterial structure comprising said method, (a) providing a hydrogel comprising a fibrin network and a polysaccharide network, (b) subjecting the hydrogel of step a) to a process freeze-thaw to physically crosslink the hydrogel; and (c) subject the physically crosslinked hydrogel obtained after performing step b), to lyophilization. The invention also relates to the biomaterial structure that can be obtained by the method as defined above, as well as to said biomaterial structure for use to increase, partially or completely restore or replace the functional activity of a diseased or oral mucosa. damaged. |