| abstract |
Pharmacological compositions containing a hydroxamic acid derivative selected from (2S) -2 - ((4 - ((4- (1S) -1,2-dihydroxyethyl) phenyl) ethynyl) benzoyl) (methyl) amino) -N-hydroxy -N´, 2-dimethylmalonami da, (2S) -2 - ((4 - ((4- (1R) -1,2-dihydroxyethyl) phenyl) ethynyl) benzoyl) (methyl) amino) -N-hydroxy-N ´, 2-dimethylimalonamide and (2S) -N-hydroxy-2 - ((4 - ((4 - ((1S) -1-hydroxy-2-methoxyethyl) phenyl) ethinyl 1) benzoyl) (methyl) amino) - N ', 2-dimethylmalonamide or a salt of the derivatives and an antibiotic substance are useful in the treatment of Gram-negative bacterial infections. |