| abstract |
A novel grape seed extract is enriched in procyanidins, has total polyphenols of less than 70% and has a low degree of polymerization (dp). Other fractions of the extract have minimal polyphenols, fiber and protein, but contain more than 90% sugars. In some specific examples, the individual extracts are obtained by sequential ultrafiltration of a water extract from the grape seeds. A first ultrafiltration provides a first permeate (Fraction A) enriched in sugars that is useful as a flavoring, and a first retained. The first retentate is reconstituted and subjected to a second ultrafiltration at a higher molecular weight cut to produce a second permeate (Fraction B) that is enriched in low molecular weight polyphenols, and a second retentate (Fraction C) that is enriched in the seed fiber. The Fractions are individually suitable for different nutraceutical products, or they can be combined with each other in any combination and / or with other nutraceutical agents to improve vascular and cognitive health. |