| abstract |
The present invention relates to benzimidazol-2-amines with the general formula (I): (see Formula) where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 are for example as defined here. Methods to elaborate them. Intermediate compounds useful for its elaboration. Compositions and pharmaceutical combinations that comprise them. Its use in the manufacture of pharmaceutical compositions useful in the prophylaxis or treatment of various diseases, particularly neoplasms, in the form of individual agents or in combination with other active ingredients. |