abstract |
The compounds of Formula (I) (see Formula) or salts thereof are described, wherein: HET is a heteroaryl selected from pyrazolyl, indolyl, pyrrolo [2,3-b] pyridinyl, pyrrolo [2,3-d ] pyrimidinyl, pyrazolo [3,4-b] pyridinyl, pyrazolo [3,4-d] pyrimidinyl, 2,3-dihydro-1 H -pyrrolo [2,3-b] pyridini lo, imidazo [4,5-b] pyridinyl and purinyl, wherein the heteroaryl is substituted with Ra and Rb; and R1 and R2 are defined herein. Methods for using such compounds as IRAK4 modulators, and pharmaceutical compositions comprising such compounds are also described. These compounds are useful for treating, preventing or slowing inflammatory and autoimmune diseases. |