| abstract |
The present invention relates to pharmaceutical agents useful for therapy and / or prophylaxis in a mammal, and in particular to NF-kB inducing kinase inhibitors (NIK - also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders; The invention also relates to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds or pharmaceutical compositions to prevent or treat diseases such as cancer, inflammatory disorders, metabolic disorders, including obesity. and diabetes, and autoimmune disorders. |