http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2015015893-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0459 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 2014-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_520f33558afc03a605e7c82123805a40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94db340f489be26a21d28a776465b728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d361c8cd448909c6953bdb08cd51e78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1587176c842f346fcdb10c856e049df |
| publicationDate | 2016-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2015015893-A |
| titleOfInvention | 2-PHENYLIMIDAZO [1,2-A] PYRIMIDINS AS IMAGE FORMING AGENTS. |
| abstract | The present invention relates to a compound with the general formula (see Formula) in which R1 is phenyl, optionally substituted by one or two substituents, selected from 3H, halogen, lower alkyl, dimethylamino, NHC (O) -alkyl, C (O) Lower alkyl, lower alkoxy, OC (3H) 3, O11CH3, OCH2CH218F, lower alkoxy substituted by halogen, hydroxy, lower alkyl substituted by hydroxy, S-lower alkyl, or by a heterocyclyl group; or is benzo [d] [1,3-dioxol-5-yl, 2,3-dihydrobenzo [bl [1,4] dioxin-6-yl, indolin-2-one, or is heteroaryl, selected from the group consisting of in thiophenyl, benzofuranyl, benzothiophenyl, pyrazinyl, or benzothiazolyl; R2 is hydrogen, lower alkyl or lower alkyl substituted by halogen; R3 is lower alkyl, C (3H) 3.11CH3, lower alkyl substituted by halogen, - (CH2) 2-O-lower alkyl substituted by halogen or cycloalkyl; or R2 and R3 together with the N atom to which a ring containing -CH2CH2CHRCH2CH2-, -CH2CH2CH2CH2-, -CH2CH2CH2-, -CH2CH2-NR-CH2CH2-, -CH2CH2-O-CH2CH2-, -CH2CH2CHRCH2- are attached , -CH2CHRCH2- or (see Drawing) R is hydrogen, halogen, lower alkyl substituted by halogen or lower alkoxy; or a pharmaceutically acceptable acid addition salt, a racemic mixture or its corresponding enantiomer and / or optical isomer thereof. The compounds are suitable as imaging tools, which can improve diagnosis by identifying potential patients with excess tau aggregates in the brain, which will likely develop Alzheimer's disease. |
| priorityDate | 2013-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.