| abstract |
The present invention belongs to the technical field of medicines, and refers to a crystalline form of a compound used as a mineralocorticoid receptor antagonist and a method of preparing it, and in particular, to a method for preparing a 2-chloro compound. 4 - {(3S, 3aR)] - 3-cyclopentyl-7- (4-hydroxypiperidine-1-carbonyl) -3,3a, 4,5-tetrahydro-2H- pyrazolo [3,4-fjquinoline-2-yl] benzonitrile of the formula (I), a crystalline form thereof, a method of preparing the crystalline form, and the use of the crystalline form in the preparation of drugs for the treatment and / or prevention of kidney injury or cardiovascular disease . (see Formula). |