abstract |
The present invention relates, in part, to nucleic acids encoding proteins, therapeutic agents comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, kits and devices for transfecting, performing genetic editing and reprogramming. cells, and cells, organisms and therapeutic agents produced using these methods, kits and devices. Methods and products to alter the DNA sequence of a cell are described, as well as methods and products to induce cells to express proteins, through the use of synthetic RNA molecules. Therapeutic agents comprising nucleic acids encoding gene editing proteins are also described. |