abstract |
A pharmaceutical oral rapid disintegration form comprising functionalized natural or synthetic calcium carbonate, at least one active ingredient and at least one disintegrant, where the functionalized natural or synthetic calcium carbonate is a reaction product of natural calcium carbonate or synthetic with carbon dioxide and one or more acids, where carbon dioxide is formed in situ by acid treatment, and / or is supplied from an external source, and where the tablet dissolves in less than 20 seconds when introduced In an aqueous environment. |