abstract |
GCF-8 inhibitors of the formula (I), and pharmaceutically acceptable salts thereof, are described, wherein n, R1, R2, R5, R6, X and Z are defined herein. Pharmaceutical compositions comprising the same are also provided. Such compounds and compositions are useful in methods for inhibiting GCF-8 in a cell and methods for treating a patient suffering from a disease or disorder, where the patient would therapeutically benefit from an increase in muscle tissue mass or resistance. . |