abstract |
The present invention relates to a process for the preparation of loforminol, a contrast agent useful in x-ray imaging. More particularly, the invention relates to the preparation of loforminol from a mixture of compound comprising 1-formylamino -3,5-bis (2,3-bis (formyloxy) propan-1-ylc arbamoyl) -2,4,6-trioodobenzene by a process comprising in situ hydrolysis and a bis-alkylation. |