| abstract |
The present invention relates to a process for the preparation of iodinated X-ray contrast agents and in particular to key intermediates thereof. More particularly, the invention relates to a manufacturing process for preparing a mixture of compound comprising 1-formylamino-3,5-bis (2,3-bis (formyloxy) propan-1-ylcarbamoyl) -2.4 , -trioodobenzene, a key intermediate in the process to prepare loforminol. In addition, the invention relates to a process for preparing loforminol, a contrast agent useful in X-ray imaging. |