| abstract |
In general, the present description refers to compositions comprising a crosslinked polymer with cation bonds comprising monomers containing carboxylic acid groups and groups that reduce pKa that include electron acceptor substituents such as halide atoms (e.g., fluorine ) and a base, in which the polymer optionally contains less than about 20,000ppm of cations other than hydrogen and in which the base is present in an amount sufficient to provide about 0.2 equivalent to about or, 95 base equivalents per equivalent of carboxylic acid groups in the polymer. The present description also refers to methods for preparing said compositions and methods for using them to treat various diseases or disorders. |