| abstract |
Pharmaceutical compositions for the treatment of pain are provided, for example short-term pain, the compositions comprising a mixture comprising: (a) alfentanil microparticles, or a pharmaceutically acceptable salt thereof, the microparticles being present on the surfaces of carrier particles bigger; (b) a weak water soluble base; and (c) a compound that is a weak acid, the acid being presented in intimate mixing with the alfentanil microparticles or the salt thereof. The composition may further comprise a disintegrant. The acid is preferably citric acid. |