| abstract |
In general, a tissue thickness compensator may comprise a first layer comprising a first biocompatible material sealed in a water impermeable material and a second layer comprising a second biocompatible material comprising at least one encapsulation, wherein the first biocompatible material expands when it comes into contact with a fluid; The tissue thickness compensator may comprise a hemostatic agent, an anti-inflammatory agent, an antibiotic agent, an antimicrobial agent, an anti-adhesion agent, an anticoagulant agent, a medicament and / or pharmaceutically active agent; encapsulation may comprise a biodegradable material to degrade in vivo and / or in situ; the tissue thickness compensator may comprise a hydromel; The reaction product may comprise a composition capable of swelling upon contact with fluid; The articles of manufacture comprise the tissue thickness compensator and the methods for making and using the tissue thickness compensator are also described. |