| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2012-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca7563454995d1cdff793006830bdd93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d43b4f9a448092f0716df180c21d0dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaf724d140c1c1d8e8109508965985f4 |
| publicationDate |
2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2014010943-A |
| titleOfInvention |
STABILIZED PROTEINS ENGINEERING. |
| abstract |
Here, conformationally stabilized ubiquitin proteins and methods for their use are provided to identify agents that bind to the stabilized ubiquitin protein or that bind to a protein that interacts with or processes the stabilized form of the ubiquitin protein. Methods for the detection of conformationally stabilized proteins that have an increased binding affinity to a ligand in comparison to the binding affinity of the wild-type form of the protein to the ligand are also provided herein. |
| priorityDate |
2012-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |