| abstract |
A method for the preparation of glycerol esters (triglycerides) of medium chain monocarboxylic fatty acids consisting of the reaction of the free fatty acid precursor and glycerol in the presence of a catalyst under partial vacuum is described; the process preferably uses a metal catalyst such as an oxide or a tungsten, molybdenum, calcium, zinc, chromium or magnesium chloride; the method of the invention allows the preparation with high yield and high purity (> 99.5%) of the final triglyceride; The method herein allows the formation of triglycerides without solvent; Triglyceride obtained by the method and pharmaceutical composition containing triglyceride as an excipient or as an active ingredient is also contemplated. |