abstract |
The present invention relates to extended recombinant polypeptide compositions (XTEN), conjugate compositions comprising XTEN and XTEN linked to crosslinking agents for conjugation in pharmacologically active payloads, methods for performing highly purified XTEN, methods for making XTEN conjugates -linker and XTEN-payload, and methods for using the compositions of XTEN-crosslinking agent and XTEN-payload. |