| abstract |
The invention provides an antibody directed to a cancer antigenic protein, which is specifically expressed on the surface of a cancer cell and the use of the antibody as a therapeutic and / or preventive agent for cancer. Specifically, the present invention provides: an antibody or a fragment thereof having immunological reactivity with a partial CAPRIN-1 polypeptide, comprising an amino acid sequence represented by SEQ ID No .: 5 or an amino acid sequence having a sequential identity of 80% or greater with said amino acid sequence, and a pharmaceutical composition for the treatment and / or prevention of cancer, which comprises the antibody or a fragment thereof as the active ingredient. |