abstract |
The present invention relates to the preparation of cyclopropane derivatives, in particular 2-amino-9- [[(1S, 2R) -1,2- bis (hydroxymethyl) cyclopropyl] methyl] -4,8-dihydro-1H- purin-6-one, especially by the intermediate compound of [(1S, 7R) -4-phenyl-3,5-dioxabicyclo [5.1.0] octan-1-yl] methanol. |