| abstract |
Novel trihydrated polymorphic forms of the sadistic salt of 4-tert-butyl-N- [4-chloro-2- (1-oxy-pyridine-4-carbonyl) -fenilibencenesulfonamide are described. One embodiment of the present invention is directed to a crystalline form of the sadistic salt of 4-tert-butyl-N- [4-chloro-2- (1-oxy-pyridine-4-carbonyl) -25 phenyl] -benzenesulfonamide ( hereinafter "Compound A _ crystalline trihydrate form I"), wherein the crystalline form is characterized by a powder X-ray diffraction pattern comprising diffraction angles (28 °), when measured using Cu Ka radiation, at approximately 4.5, 9.0 13.6, 13.9, 15.8, 17.8, 18.2, 18.5, 19.1, 19.9, 20A, 21.2, 22.1, 22.7, 24.3, 25.0, 25.6, 26.2, 26.8, 27.3, 27.6, 28.0, 28.8 and 30.8. |