| abstract |
The present invention provides pharmaceutically acceptable compounds and salts that are tyrosine kinase inhibitors, in particular BLK, BMX, EGFR, HER2, HER4, ITK, JAK3, TEC, Btk and TXK, and, therefore, are useful for treatment. of diseases that can be treated by the inhibition of tyrosine kinases such as cancer and inflammatory diseases, such as arthritis, and the like. Also provided are pharmaceutical compositions containing such compounds and pharmaceutically acceptable salts, and processes for preparing such compounds and pharmaceutically acceptable salts. |