http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2013010280-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2012-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19159da1d90f18368c485c59e3f6a004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fc13c3219a0f9817a1eb2c82ed3419d |
| publicationDate | 2013-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2013010280-A |
| titleOfInvention | DERIVATIVES OF 3,4-DIHYDROPIRROLO [1,2-A] PIRAZIN-1-ILAMINE USED AS BETA-SECRETASE (BASE) INHIBITORS. |
| abstract | The present invention relates to 3,4-dihydropyrrolo [1,2-a] pyrazin-1-ylamine derivatives as beta-secretase inhibitors, also known as the enzyme that cleaves the amyloid precursor protein by the beta site, BACE , BACE1, Asp2 or memapsin 2; The invention also relates to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions to prevent and treat disorders in which beta-secrete participates, such as Alzheimer's disease. (EA), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down syndrome, dementia associated with stroke, dementia associated with Parkinson's disease or dementia associated with beta-amyloid. |
| priorityDate | 2011-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 227.