| abstract |
The present invention provides a diaminopyrimidine derivative or its acceptable pharmaceutical salt, a process for its preparation, a pharmaceutical composition comprising it and the use thereof. The diaminopyrimidine derivative or its acceptable pharmaceutical salt functions as a 5-HT4 receptor and therefore can be applied in a useful way to prevent or treat dysfunction in gastrointestinal mobility, one of the gastrointestinal diseases, such as gastroesophageal reflux disease (GERD), constipation , irritable bowel syndrome (lBS), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, or diabetic gastric atony. |