| abstract |
The invention relates to the compounds of the general formula I wherein R is heteroaryl optionally substituted with R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted with R8; or R is X where X is -NR11R12; and pharmaceutically acceptable salts, hydrates or solvates thereof, for use alone or in combination with one or more other pharmaceutically active compounds in therapy, to prevent, treat or improve disorders or conditions that respond to oxidative burst stimulation. of neutrophils, which respond to the stimulation of the release of IL-8 from keratinocytes or that respond to the induction of necrosis. |