| abstract |
The invention provides a method for inhibiting vascular hyperpermeability in an animal in need thereof. The method comprises administering an effective amount of a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically acceptable salt of any of these to the animal, wherein the diketopiperazine has the formula set forth in the specification. The invention also provides a method for modulating the cytoskeleton of an endothelial cell in an animal. The method comprises administering an effective amount of a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically acceptable salt of any of these to the animal, wherein the diketopiperazine has the formula set forth in the specification. The invention also provides equipment. The equipment comprises a diketopiperazin, a prodrug of a diketopiperazine or a pharmaceutically acceptable salt of any of these for the animal, wherein the diketopiperazine has the formula set forth in the specification. |