| abstract |
The invention provides compositions and methods for the treatment of mild cognitive impairment (MI), and to inhibit, reduce, delay and / or prevent the progression of MCI to Alzheimer's disease. The methods involve administering an effective amount of one or more compounds selected from the group consisting of tropisetron, disulfiram, honokiol and nimetazepam. The methods are also useful for prophylactic and therapeutic treatment of amyloidogenic diseases, including Alzheimer's disease. |