| abstract |
This invention has to do with the cis-5 and trans-5 isomers of geranyl-geranyl-acetone, preferably, these synthetic isomers and pharmaceutical compositions containing said isomers. Other aspects of this invention have to do with the use of geranyl-geranyl-acetone and its isomers in methods to inhibit neuronal death, increase neuronal activity and increase axon growth and cell viability. Geranyl-geranyl-acetone is an antiulcer drug that is used commercially and in clinical situations. The GGA has also shown that it exerts cytoprotective effects on a variety of organs, such as the eye, the brain and the heart. |