| abstract |
The present invention provides compounds having the general formula (I): and the pharmaceutically acceptable stereoisomers, tautomers, or salts thereof, wherein R1, R2, R3, R4 and n are as defined herein, the compositions that include the compounds and the method of using the compounds to treat a disease or disorder mediated by the isoform p110 delta of the kinase PI3 selected from immune disorders, cancer, cardiovascular disease, viral infection, inflammation, metabolic disorders / endocrine function and neurological disorders . |