| abstract |
A crystal of 1- (4-methoxybutyl) -N- (2-me tiIpropyl) -N - [(3 S, 5 R) -5- (morfoiln-4-iicarbonyl) piperidin-3-yl] hydrochloride is described -1H-benzimidazol-2-carboxamide that has excellent renin inhibitory activity that is useful as a preservative or other therapeutic agent for types of organ dysfunction and the like, which are derived from high blood pressure and hypertension. 1 - (4-Methoxybutyl) -N- (2-methyl propi 1) -N - [(3S, 5R) -5- (morpholin-4-ylcarbonhl) piperidin-3-yl] -1H- hydrochloride crystal Benzimidazol-2-carboxamide has a powder X-ray diffraction pattern, where the lattice spacing (d) of the powder X-ray diffraction pattern has characteristic peaks that appear in the vicinity of 26.43 ± 0.2, 7.62 ± 0.2 and 4.32 ± 0.2 angstroms. |