| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F17-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F17-02 |
| filingDate |
2011-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bcd9931e09219571159006d87be12ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64b436b076fc885f77d370f8d50f2592
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5d89f7cc3f2462f7e5b353e11bb2a82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c632fbe4ce926ea060d976ddddbaa04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef401939cd2487544d7d21600609ade8 |
| publicationDate |
2013-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2012014473-A |
| titleOfInvention |
PROCEDURE OF SYNTHESIS OF THE FERROQUINA BY CONVERGENT REDUCING AMINATION. |
| abstract |
The invention relates to a method of synthesis of ferroquine of formula (F) or of its metabolite of formula (Fm): comprising a reductive amination reaction, comprising such reaction: (i) a condensation step of the aldehyde-amino ferrocene of formula (1), in which R represents a hydrogen atom or a methyl group, with 7-chloroquinolin-4-amine of formula (2) as shown below, followed by (ii) of a step of reduction of the condensation product obtained in the previous stage (iii) after a stage of hydrolysis of the reaction medium in the presence of an aqueous solution of ammonia or citric acid. |
| priorityDate |
2010-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |