http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2012013958-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6455 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate | 2011-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02a31faf57946465a149a34bd1615ab3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_632105c1735845c86984df123641f00d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_887a8cdbaa15f1f7e59078dc1733d468 |
| publicationDate | 2013-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2012013958-A |
| titleOfInvention | PENETRATOR PEPTIDES OF THE CELLS AND USES OF THE SAME. |
| abstract | The present invention relates to a peptide molecule capable of being internalized in a cell, wherein the peptide molecule (a) has a length of at least 10, preferably at least 15 amino acid residues; (b) comprises in its primary amino acid sequence at least 25% preferably at least 30% positively charged amino acid residues; and (c) it is internalized in a cell with an efficiency that is at least 80%, preferably at least 90% of the internalization efficiency of the TAT peptide having the amino acid sequence GRKKRRQRRRPPQ. The invention also relates to a corresponding nucleic acid molecule that codes for this peptide as well as to a composition comprising at least this peptide that is used to any of the group consisting of one or more nucleic acid molecules, one or more peptides or proteins, one or more small molecules, and one or more nanoparticles, wherein the binding is achieved by a bond selected from the group consisting of a covalent bond and a non-covalent bond. Additionally, the invention relates to a method for detecting the internalization behavior of this peptide or composition, which comprises (a) administering the peptide or composition to one or more cells; (b) detect the internalization of the peptide or composition. Finally, the invention relates to the use of this peptide or composition for the transformation or transfection of one or more cells as well as in the prevention and / or treatment of a condition selected from the group consisting of cancer, immune diseases, cardiovascular diseases, diseases Neural, infections, and inflammatory diseases. |
| priorityDate | 2010-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 399.