http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2012013305-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-5421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-5412 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate | 2011-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7203ff904ad5d07531926acda33f516 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70c3aa39e1732964b76a4494578136e0 |
publicationDate | 2013-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | MX-2012013305-A |
titleOfInvention | COMBINED THERAPY AND METHOD FOR EVALUATING TREATMENT RESISTANCE. |
abstract | The present invention relates to a method for determining a patient's resistance to treatment with 2,2-dimethyl-N - ((S) -6-oxo-6, 7-dihydro-5H-dibenzo [b, d] azepin -7-yl) -N '- (2, 2, 3, 3, 3-pentafluoro-propyl) -malonamide by quantifying the levels of a biomarker or biomarkers found in a biological sample obtained from the patient, the biomarker is 1L6 and / or 1L8. The present invention also relates to a combination therapy for a patient suffering from a proliferative disorder comprising administration to the patient of 2,2-dimethyl-N - ((S) -6-oxo-6, 7- dihydro- 5H-dibenzo [b, djazepin-7-yl) -N '- (2, 2, 3, 3, 3-pentafluoro-propyl) -malonami gives and an anti-1L6 and / or anti1L8 agent. |
priorityDate | 2010-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.