| abstract |
The heteroaromatic compounds of Formula I: (See Formula) (I) are inhibitors of HIV reverse transcriptase, in which R1, R2, R3, R4 and R5 are defined herein; the compounds of formula I and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, prophylaxis and treatment of HIV infection and prophylaxis, delayed onset or progression, and treatment of AIDS; The compounds and their salts can be used as ingredients in pharmaceutical compositions, optionally together with other antivirals, immunomodulators, antibiotics or vaccines. |