| abstract |
Vectors for vaccines that include an antigenic polypeptide and an HMGB1 polypeptide that are present on the surface of the vaccine vector. Compositions comprising vectors for vaccines and include a pharmaceutically acceptable carrier, conveniently a vehicle for oral or nasal administration. Methods for enhancing immune responses, in particular, an antibody immune response and conveniently an IgA response, by administering to a subject the vectors for vaccines or compositions set forth herein. |