abstract |
A liquid formulation is described that allows long-acting G-CSF conjugates, which have improved durability and stability in vivo, to be stable when stored for a prolonged period of time. It comprises a stabilizing composition characterized by a buffer solution and mannitol. Being free of human serum albumin and other factors potentially harmful to the body, the liquid formulation is free from concerns about viral infections and guarantees excellent storage stability for long-acting G-CSF conjugates. |