| abstract |
A composition is provided to improve blood circulation, which comprises an extract of Lindera obtusiloba as an active ingredient, and more specifically, with a pharmaceutical composition and a healthy functional food to prevent and treat thrombotic disorders, improving blood circulation, which comprises an extract of Lindera obtusiloba as an active ingredient. The Lindera obtusiloba extract of the present invention and a purified crude product thereof can be obtained through extraction using various solvents such as water, ethanol, methanol, butanol, etc. Since the extract and the purified crude product not only have an excellent inhibitory effect on platelet aggregation induced by various inductions of aggregation in vitro, but also an excellent inhibitory effect on rapid thrombus formation in vivo, they can be useful to prevent and treat diseases caused by blood circulation disorders, such as thromboembolism, etc. |