abstract |
A process is provided herein for the preparation of N- (5-tert-butyl-isoxazol-3-yl) -N '- {4- [7- (2-morpholin-4-yl-ethoxy) imidazo- [ 2,1-b] [1,3] benzothiazol-2-yl] feni} urea, or a pharmaceutically acceptable salt, solvate, hydrate or polymorph thereof. N- (5-tert-butyl-isoxazol-3-iI) -N '- {4- [7- (2-morphoIin-4-i-ethoxy) midazo- [2,1-b] [1,3] -benzothiazol-2-yl] phenyl} urea is useful for treating, preventing and / or administering diseases or conditions, including but not limited to, proliferating diseases, diseases mediated with FLT-3, and cancers. N- (5-tert-butyl-isoxaz ol-3-yl) -N '- {4- [7- (2-morpho-4-yl-ethoxy) -imidazo- [2,1-b] [1, 3] ben zothiazol-2-iI] phenyl} urea is represented by the mentioned structure. |