http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2012003041-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0597f9c318d2aeca86db94711c516383 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502 |
filingDate | 2010-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47e1c33131f6eb7dd329bfd1d3d14251 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ff796148e25daac7b697321130094f2 |
publicationDate | 2012-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | MX-2012003041-A |
titleOfInvention | USE OF N- (4 - ((3- (2-AMINO-4-PIRIMIDINIL) -2-PIRIDINIL) OXI) PHENYL) -4- (4-METHYL-2-TIENILE) -1-FTALAZINAMINE IN CANCER TREATMENT RESISTANT TO ANTIMITOTIC AGENT. |
abstract | The present invention relates to methods for using the compound, N- (4 - ((3- (2-amino-4-pyrimidinyl) -2-pyridinyl) oxy) phenyl) -4- (4-methyl-2-thienyl) ) -1-phthalazinamine or a pharmaceutically acceptable salt thereof, to treat cancers, including solid tumors, that have become resistant to treatment with chemotherapeutic agents, including anti-mitotic agents such as taxanes, and / or other anti-cancer agents , including aurora kinase inhibitors. The invention also includes methods for treating refractory cancers for such treatments by administering a pharmaceutical composition, which comprises the compound for a subject with cancer. |
priorityDate | 2009-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 260.