| abstract |
Octasaccharides N-acyl activators of the FGF receptors, which respond to formula (I): in which R1 represents an O-alkyl group optionally substituted with one or more aryl or cycloalkyl groups, R2 represents an OSO3 or hydroxyl group, R3 represents an alkyl, cycloalkyl or alkyl-cycloalkyl group, and R4 represents a disaccharide of formula (II), R6 represents a disaccharide of formula (III) and R8 represents a disaccharide of formula (IV), in which R5, R7 and R9 represent the OSO3 or hydroxyl groups: Their preparation and their application in therapeutics. |