| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ea17ba87480b776cce77451f86b25bb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-84 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-415 |
| filingDate |
2010-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d02cafa024a609da039578ce64fca655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ffe7bfdea70fe1328990b7500ab975c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_804f5019e45664da25eacddf5d783982
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1feb36c8e75fe8185de26f1eceeb3d41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70ed7ba4be4672ae32d5dc29cb2fb49b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65a8ea404ea01d4dd669f4f56fb3ef3a |
| publicationDate |
2012-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2011013680-A |
| titleOfInvention |
CLONATION, EXPRESSION OF YEAST, PURIFICATION AND BIOLOGICAL ACTIVITY OF THE EXTENSION REGION OF THE ALFA-PRIMA SUBUNITY OF THE GLOBULIN 7S OF SOYA INCLUDED IN THE HOSTG2 CELLULAR HOMEOSTASIS. |
| abstract |
A truncated form of the a '(ea') chain, 7S soy globulin, which acts to control homeostasis of cholesterol and triglycerides in in vitro and in vivo models was cloned and expressed in the yeast Pichia pastoris; the recombinant polypeptide encompassed 142 amino acid residues on the Nterminal side and included the N-terminal extension region of the alpha 'subunit of soybeans; The ea 'polypeptide was purified by conventional biochemical techniques and its potential to modulate the activity of the LDL receptor was evaluated in a human hepatoma cell line (Hep G2) by monitoring the uptake and degradation of labeled LDL. |
| priorityDate |
2009-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |