abstract |
The present invention relates to Janus kinase (JAK) 3- [4- (7H-pyrrolo [2,3-d] pyrimidin-4-yl) -1H-pyrazol ol-1-yl] octanonitrile or 3 inhibitors - [4- (7H-pyrrolo [2,3-d] pyrimidin-4-yl) -1H- pyrazol-1-yl] heptanonitrile, as well as its compositions and methods of use, which are useful in the treatment of JAK associated diseases including, for example, inflammatory and autoimmune disorders, skin disorders, cancer and other diseases. |